Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo | PNAS
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer | Cell Death Discovery
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis | Cell Death & Disease
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Pevonedistat - an overview | ScienceDirect Topics
Pevonedistat - an overview | ScienceDirect Topics
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation - ScienceDirect
A model for the role of MLN4924 in mtOr signaling inactivation.... | Download Scientific Diagram
Cancers | Free Full-Text | Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer
Model for redox regulation of ENaC where reactive ROS or MLN4924... | Download Scientific Diagram
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy | Antioxidants & Redox Signaling
IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis
Schema of the mechanism for MLN4924 enhancing ATRA-induced... | Download Scientific Diagram
Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma - Shida Xiong, Wei Huang, Xiaoqiang Liu, Qian Chen, Yi Ding, Haoxuan Huang, Ru Zhang,
