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Wake up the Sleeping Beauty - Transposons in gene therapy: How do they compare to other genome modifying tools? - Biopharma Excellence
Abiogenesis - A transposable element (TE or transposon) is a DNA sequence that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and
![Caption: Ribbon diagram of the crystal structure of the Tn5 transposase/DNA complex, with the short pieces of DNA from the crystal structure extended to illustrate how the ends of the transposon bound to the protein/DNA complex are part of a continuous ... Caption: Ribbon diagram of the crystal structure of the Tn5 transposase/DNA complex, with the short pieces of DNA from the crystal structure extended to illustrate how the ends of the transposon bound to the protein/DNA complex are part of a continuous ...](https://news.wisc.edu/newsphotos/images/Fig1_Tn5_schematic.jpg)
Caption: Ribbon diagram of the crystal structure of the Tn5 transposase/DNA complex, with the short pieces of DNA from the crystal structure extended to illustrate how the ends of the transposon bound to the protein/DNA complex are part of a continuous ...
![Structural basis of seamless excision and specific targeting by piggyBac transposase | Nature Communications Structural basis of seamless excision and specific targeting by piggyBac transposase | Nature Communications](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-020-17128-1/MediaObjects/41467_2020_17128_Fig1_HTML.png)
Structural basis of seamless excision and specific targeting by piggyBac transposase | Nature Communications
![Summary of transposition mechanisms. Transposition mechanisms for major... | Download Scientific Diagram Summary of transposition mechanisms. Transposition mechanisms for major... | Download Scientific Diagram](https://www.researchgate.net/publication/331337557/figure/fig1/AS:730357460660229@1551142196584/Summary-of-transposition-mechanisms-Transposition-mechanisms-for-major-eukaryotic.png)
Summary of transposition mechanisms. Transposition mechanisms for major... | Download Scientific Diagram
![Structure and mechanism of transposition of the piggyBac transposon.... | Download Scientific Diagram Structure and mechanism of transposition of the piggyBac transposon.... | Download Scientific Diagram](https://www.researchgate.net/profile/Paul-Brindley/publication/5856022/figure/fig1/AS:667208216760322@1536086243261/Structure-and-mechanism-of-transposition-of-the-piggyBac-transposon-A-Schematic.png)